- Arlington Road – Eastbourne, BN21 1DH
- Bolton Road – Eastbourne, BN21 3JY
- Bridgeside – Western Road, Hailsham, BN27 3DG
- Lighthouse – College Road, Eastbourne, BN21 4HY (including Ian Gow Memorial Health Centre)
- Downlands – High Street, Polegate, BN26 6AE
- Enys Road – Eastbourne, BN21 2DQ
- Green Street – Eastbourne, BN21 1RR
- Grove Road – Eastbourne, BN21 4TX
- Hailsham Medical Group – Hailsham (Seaforth Farm, Vicarage Lane, BN27 1BH & Vicarage Field, BN27 1BE)
- Harbour – Pacific Drive, Sovereign Harbour North, Eastbourne, BN23 6DW
- Herstmonceux Integrative Health Centre – Hailsham Road, Herstmonceux, BN27 4JX
- Manor Park – High Street, Polegate, BN26 5DJ
- Old School – Church Street, Seaford, BN25 1HH (including Alfriston & East Dean)
- Park Practice – Broadwater Way, Hampden Park, BN22 9PQ
- Princes Park (Sovereign) – Wartling Road, Eastbourne, BN22 7PG
- Quintin – Hawkswood Road, Hailsham, BN27 1UG (including Battle Road and Punnetts Town)
- Seaford Medical Practice – Dane Road, Seaford, BN25 1DH
- Seaside – Eastbourne, BN22 8DR
- Stone Cross – Mimram Road, BN24 5DZ (including Westham & Pevensey Bay)